ELK3

Across TCGA cell cohorts, ELK3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,024 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ELK3-associated GO terms across cancer lineages are Regulation of cell-matrix adhesion, Positive regulation of focal adhesion assembly, and Wound healing. Each is linked with ELK3 in more than 17 cancer types. Because this analysis shows association rather than direction, both ELK3-to-partner and partner-to-ELK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell-matrix adhesion grouped by ELK3-low versus ELK3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ELK3→partner) and Y-score (partner→ELK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of cell-matrix adhesion →	+0.136	+1.401	<.001	<.001	2	18
LUNG_NSCLC_LUSC	Positive regulation of focal adhesion assembly →	+0.226	+2.448	<.001	<.001	3	17
OESOPHAGUS	Wound healing →	+0.121	+2.057	<.001	<.001	3	15
BREAST	Foam cell differentiation →	+0.288	+1.161	<.001	<.001	3	15
BONE	Regulation of cell-substrate junction assembly →	+0.148	+1.353	<.001	<.001	2	16
BONE	Regulation of focal adhesion assembly →	+0.148	+1.353	<.001	<.001	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,024 associations by consensus.

Regulation of cell-matrix adhesion by ELK3 expression — BONE

Explore this box plot interactively →