Across TCGA pan-cancer cohorts, ELK2BP RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of ELK2BP’s most consistent transcriptional readouts.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where ELK2BP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ELK2BP is over-expressed in tumor.
UCEC and HNSC are the cancer types where ELK2BP tumor–normal differential expression is most reproducible.