ELK1

Across TCGA patient cohorts, ELK1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,090 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELK1-associated genes across cancer lineages are SFRP5, MIR554, and LINC02816. Each is linked with ELK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELK1-to-partner and partner-to-ELK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ELK1 versus SFRP5 in GBM, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELK1→partner) and Y-score (partner→ELK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SFRP5 →	-1.184	-0.381	.001	<.001	3	2
UCEC	MIR554 →	-1.063	-0.337	.004	.002	3	2
OV	LINC02816 →	-0.593	-0.379	.006	.003	3	2
CCRCC	TNC →	-2.255	-0.920	.002	.008	3	2
BRCA	NES →	+1.306	+0.388	<.001	<.001	3	2
UCEC	ITM2C →	+0.966	+0.349	.005	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,090 associations by consensus.

ELK1 vs SFRP5 — GBM

Explore this scatter interactively →