ELF5

Across TCGA cell cohorts, ELF5 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,197 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible ELF5-associated GO terms across cancer lineages are Response to indole-3-methanol, Cellular response to indole-3-methanol, and Peptide transport. Each is linked with ELF5 in more than 5 cancer types. Because this analysis shows association rather than direction, both ELF5-to-partner and partner-to-ELF5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to indole-3-methanol grouped by ELF5-low versus ELF5-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ELF5→partner) and Y-score (partner→ELF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Response to indole-3-methanol →	+0.182	+1.908	<.001	.002	3	6
URINARY_TRACT	Cellular response to indole-3-methanol →	+0.206	+1.486	<.001	.004	3	6
URINARY_TRACT	Peptide transport →	-0.094	-1.688	.001	.007	3	6
BREAST	Negative regulation of potassium ion transmembrane transporter activity →	+1.432	+2.300	<.001	<.001	3	5
BREAST	Negative regulation of voltage-gated potassium channel activity →	+1.432	+2.300	<.001	<.001	3	5
PANCREAS	Positive regulation of cell communication by electrical coupling →	+1.280	+0.833	<.001	.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,197 associations by consensus.

Response to indole-3-methanol by ELF5 expression — BREAST

Explore this box plot interactively →