ELF5

Across TCGA cell cohorts, ELF5 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ELF5-associated genes across cancer lineages are FAM24A, KCNA4, and KRTAP21-2. Each is linked with ELF5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELF5-to-partner and partner-to-ELF5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM24A grouped by ELF5-low versus ELF5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELF5→partner) and Y-score (partner→ELF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FAM24A →	+0.083	+6.022	<.001	.001	3	2
BLOOD_Leukemia	KCNA4 →	+0.028	+4.922	<.001	.009	3	1
BLOOD_Leukemia	KRTAP21-2 →	+0.085	+5.539	<.001	.003	3	1
BLOOD_Leukemia	IQCF5 →	+0.135	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TLE7 →	+0.042	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

FAM24A by ELF5 expression — LARGE_INTESTINE

Explore this box plot interactively →