ELF4

Across TCGA cell cohorts, ELF4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,030 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ELF4-associated GO terms across cancer lineages are Natural killer cell proliferation, Negative regulation of inflammatory response, and Regulation of response to cytokine stimulus. Each is linked with ELF4 in more than 17 cancer types. Because this analysis shows association rather than direction, both ELF4-to-partner and partner-to-ELF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Natural killer cell proliferation grouped by ELF4-low versus ELF4-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ELF4→partner) and Y-score (partner→ELF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Natural killer cell proliferation →	+1.265	+1.393	<.001	<.001	3	18
LUNG_NSCLC_LUAD	Negative regulation of inflammatory response →	+0.059	+1.158	<.001	<.001	3	14
BREAST	Regulation of response to cytokine stimulus →	+0.063	+1.012	.001	.002	3	14
OVARY	Regulation of cytokine-mediated signaling pathway →	+0.070	+1.410	<.001	<.001	3	13
BREAST	Negative regulation of defense response →	+0.093	+1.463	<.001	<.001	3	13
SOFT_TISSUE	Wound healing →	+0.119	+1.918	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,030 associations by consensus.

Natural killer cell proliferation by ELF4 expression — BLOOD_Myeloma

Explore this box plot interactively →