ELF4

Across TCGA cell cohorts, ELF4 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ELF4-associated genes across cancer lineages are TBATA, SPRR1A, and SSX7. Each is linked with ELF4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELF4-to-partner and partner-to-ELF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBATA grouped by ELF4-low versus ELF4-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELF4→partner) and Y-score (partner→ELF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	TBATA →	+0.013	+5.369	<.001	.004	3	1
SOFT_TISSUE	SPRR1A →	+0.233	+4.930	.003	.008	3	1
SOFT_TISSUE	SSX7 →	+0.022	+5.369	<.001	.004	3	1
SOFT_TISSUE	LYZL6 →	+0.019	+5.369	<.001	.004	3	1
URINARY_TRACT	NEUROD4 →	+0.196	+5.087	<.001	.004	3	1
URINARY_TRACT	FCN2 →	+0.033	+5.087	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

TBATA by ELF4 expression — SOFT_TISSUE

Explore this box plot interactively →