ELF3

Across TCGA patient cohorts, ELF3 mutation is significantly associated with the RNA expression of many other genes, with 1,140 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible ELF3-associated genes across cancer lineages are MIR6769B, LYPLA1P1, and MTCO3P28. Each is linked with ELF3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ELF3-to-partner and partner-to-ELF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6769B grouped by ELF3-low versus ELF3-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELF3→partner) and Y-score (partner→ELF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR6769B →	+0.096	+2.981	<.001	.005	3	3
UCEC	LYPLA1P1 →	+0.081	+4.464	<.001	.005	3	3
COAD	MTCO3P28 →	+0.257	+4.209	<.001	.009	3	2
COAD	SLC20A1P3 →	+0.092	+5.917	<.001	.001	3	2
COAD	MTND5P33 →	+0.178	+5.122	<.001	.004	3	2
CESC	GAPDHP56 →	+0.015	+4.247	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,140 associations by consensus.

MIR6769B by ELF3 expression — BLCA

Explore this box plot interactively →