ELF3-AS1

Across TCGA pan-cancer cohorts, ELF3-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ELF3-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ELF3-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ELF3-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUSC show a favorable association.

KIRC, THCA, and ACC are the cancer types where ELF3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.522	0.720	<.001	126	view →
THCA	DFS	Median	II,III,IV	0.762	0.915	<.001	63	view →
ACC	OS	Median	II,III,IV	0.336	0.731	.001	56	view →
ESCA	OS	Quartile	All	0.390	0.689	.001	47	view →
LGG	DFS	Median	All	0.670	0.801	<.001	36	view →
HNSC	DFS	Median	All	0.752	0.638	.002	36	view →
LIHC	OS	Median	All	0.606	0.773	<.001	30	view →
COAD	OS	Tertile	III,IV	0.675	0.887	.004	21	view →
SKCM	DFS	Tertile	III,IV	0.127	0.355	.002	19	view →
UCEC	DFS	Median	All	0.493	0.744	.012	14	view →
PRAD	OS	Median	All	0.978	1.000	.022	14	view →
LUSC	OS	Tertile	II,III,IV	0.808	0.649	.019	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ELF3-AS1–KIRC (DFS)

Open the KIRC breakdown →