ELF3-AS1

Across TCGA pan-cancer cohorts, ELF3-AS1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of ELF3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where ELF3-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ELF3-AS1 is over-expressed in tumor, although a few such as HNSC and KICH show the opposite, repressed pattern.

BLCA, LIHC, and LUAD are the cancer types where ELF3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ELF3-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	III,IV	+1.797	<.001	11	view →
LIHC	Male	II,III,IV	+1.732	<.001	9	view →
LUAD	Male	II,III,IV	+1.505	<.001	9	view →
KIRP	All	II,III,IV	+0.938	<.001	8	view →
UCEC	All	III,IV	+1.678	<.001	6	view →
STAD	Male	All	+1.079	<.001	6	view →
BRCA	All	All	+0.835	<.001	6	view →
CHOL	Male	All	+1.933	<.001	5	view →
LUSC	All	All	+0.868	<.001	5	view →
HNSC	Female	IV	−1.489	.022	4	view →
COAD	All	All	+0.259	.021	3	view →
READ	Female	All	+0.968	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

ELF3-AS1–BLCA

Open the BLCA breakdown →