ELF2

Across TCGA cell cohorts, ELF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,617 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ELF2-associated GO terms across cancer lineages are Positive regulation of DNA repair, Positive regulation of cytoplasmic mRNA processing body assembly, and Positive regulation of double-strand break repair. Each is linked with ELF2 in more than 14 cancer types. Because this analysis shows association rather than direction, both ELF2-to-partner and partner-to-ELF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by ELF2-low versus ELF2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ELF2→partner) and Y-score (partner→ELF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of DNA repair →	+0.071	+0.640	<.001	<.001	3	15
LUNG_SCLC	Positive regulation of cytoplasmic mRNA processing body assembly →	+0.154	+0.752	<.001	<.001	3	15
SOFT_TISSUE	Positive regulation of double-strand break repair →	+0.077	+0.637	<.001	<.001	3	15
SKIN	Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.069	+0.785	<.001	<.001	3	15
SOFT_TISSUE	Negative regulation of transcription by RNA polymerase I →	+0.155	+0.636	<.001	<.001	3	14
LUNG_SCLC	DNA damage tolerance →	+0.119	+0.938	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,617 associations by consensus.

Positive regulation of DNA repair by ELF2 expression — SOFT_TISSUE

Explore this box plot interactively →