Across TCGA pan-cancer cohorts, ELAVL4-AS1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of ELAVL4-AS1’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where ELAVL4-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ELAVL4-AS1 is over-expressed in tumor, although a few such as LIHC and COAD show the opposite, repressed pattern.
LIHC, COAD, and CHOL are the cancer types where ELAVL4-AS1 tumor–normal differential expression is most reproducible.