ELAVL2

Across TCGA patient cohorts, ELAVL2 mutation is significantly associated with the RNA expression of many other genes, with 6,589 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELAVL2-associated genes across cancer lineages are RFC4, MRPS34, and E2F2. Each is linked with ELAVL2 in more than 3 cancer types. Because this analysis shows association rather than direction, both ELAVL2-to-partner and partner-to-ELAVL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RFC4 grouped by ELAVL2-low versus ELAVL2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELAVL2→partner) and Y-score (partner→ELAVL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RFC4 →	+0.517	+2.452	<.001	.001	3	4
UCEC	MRPS34 →	+0.461	+2.209	<.001	<.001	3	4
UCEC	E2F2 →	+0.743	+1.818	<.001	<.001	3	4
UCEC	RNASEH2A →	+0.432	+1.480	.001	<.001	3	4
UCEC	PSMC3IP →	+0.733	+2.010	<.001	<.001	3	4
SKCM	GINS4 →	+0.736	+2.353	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,589 associations by consensus.

RFC4 by ELAVL2 expression — SKCM

Explore this box plot interactively →