Across TCGA cell cohorts, ELANE RNA expression is significantly associated with the RNA expression of many other genes, with 8,431 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ELANE-associated genes across cancer lineages are PRTN3, AZU1, and MPO. Each is linked with ELANE in more than 13 cancer types. Because this analysis shows association rather than direction, both ELANE-to-partner and partner-to-ELANE results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELANE→partner) and Y-score (partner→ELANE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PRTN3 →	+4.639	+4.002	<.001	<.001	3	14
BLOOD_Leukemia	AZU1 →	+5.088	+3.926	<.001	<.001	3	12
BLOOD_Leukemia	MPO →	+4.099	+3.181	<.001	<.001	3	12
BREAST	TNFRSF13B →	+0.104	+0.221	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	JOSD2 →	+1.447	+0.249	<.001	<.001	3	7
SOFT_TISSUE	FBXL15 →	+1.185	+0.323	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,431 associations by consensus.

Exploration

ELANE survival (RNA) · tumor vs normal (RNA) · all ELANE data types