Across TCGA cell cohorts, ELANE RNA expression is significantly associated with the go_rna of many other GO terms, with 3,320 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ELANE-associated GO terms across cancer lineages are Neutrophil-mediated killing of fungus, Neutrophil extracellular trap formation, and Calcium-independent cell-matrix adhesion. Each is linked with ELANE in more than 16 cancer types. Because this analysis shows association rather than direction, both ELANE-to-partner and partner-to-ELANE results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ELANE→partner) and Y-score (partner→ELANE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Neutrophil-mediated killing of fungus →	+1.224	+3.936	<.001	<.001	3	17
BLOOD_Leukemia	Neutrophil extracellular trap formation →	+1.055	+3.853	<.001	<.001	3	15
SOFT_TISSUE	Calcium-independent cell-matrix adhesion →	+0.127	+0.373	<.001	.002	3	10
BLOOD_Leukemia	Keratinocyte development →	+0.753	+3.441	<.001	<.001	3	8
BLOOD_Leukemia	Antimicrobial peptide production →	+1.297	+4.000	<.001	<.001	3	7
BLOOD_Leukemia	Antimicrobial peptide biosynthetic process →	+1.297	+4.000	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,320 associations by consensus.

Exploration

ELANE survival (RNA) · tumor vs normal (RNA) · all ELANE data types