EIF6

Across TCGA patient cohorts, EIF6 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,335 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF6-associated proteins across cancer lineages are TOMM34, DDX27, and STAU1. Each is linked with EIF6 in more than 6 cancer types. Because this analysis shows association rather than direction, both EIF6-to-partner and partner-to-EIF6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF6 versus TOMM34 in LSCC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF6→partner) and Y-score (partner→EIF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TOMM34 →	+0.422	+0.540	<.001	<.001	3	7
COAD	DDX27 →	+0.429	+0.564	<.001	<.001	3	7
LSCC	STAU1 →	+0.364	+0.699	<.001	<.001	3	6
BRCA	WDR12 →	+0.364	+0.570	<.001	<.001	3	6
LSCC	NOL7 →	+0.285	+0.647	<.001	<.001	3	5
LSCC	UTP15 →	+0.270	+0.498	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,335 associations by consensus.

EIF6 vs TOMM34 — LSCC

Explore this scatter interactively →