EIF5B

Across TCGA patient cohorts, EIF5B protein abundance is significantly associated with the RNA expression of many other genes, with 15,913 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF5B-associated genes across cancer lineages are PTH1R, SYNPO2, and CNRIP1. Each is linked with EIF5B in more than 8 cancer types. Because this analysis shows association rather than direction, both EIF5B-to-partner and partner-to-EIF5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF5B versus PTH1R in OV, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF5B→partner) and Y-score (partner→EIF5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PTH1R →	-1.116	-0.289	<.001	<.001	3	9
HNSC	SYNPO2 →	-1.191	-0.213	.002	<.001	3	8
BRCA	CNRIP1 →	-1.002	-0.300	<.001	<.001	3	7
BRCA	RBMS3 →	-0.827	-0.331	<.001	<.001	3	7
CCRCC	DIPK2B →	-0.895	-0.193	<.001	<.001	3	7
BRCA	ABCA9 →	-0.804	-0.216	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,913 associations by consensus.

EIF5B vs PTH1R — OV

Explore this scatter interactively →