EIF5AL1

Across TCGA cell cohorts, EIF5AL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,240 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EIF5AL1-associated GO terms across cancer lineages are rRNA pseudouridine synthesis, Ribosome assembly, and Metaphase/anaphase transition of cell cycle. Each is linked with EIF5AL1 in more than 11 cancer types. Because this analysis shows association rather than direction, both EIF5AL1-to-partner and partner-to-EIF5AL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA pseudouridine synthesis grouped by EIF5AL1-low versus EIF5AL1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF5AL1→partner) and Y-score (partner→EIF5AL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	rRNA pseudouridine synthesis →	+0.098	+0.540	.005	.008	3	12
LARGE_INTESTINE	Ribosome assembly →	+0.081	+0.762	<.001	.003	3	11
BONE	Metaphase/anaphase transition of cell cycle →	+0.217	+0.682	.001	<.001	3	11
BONE	Regulation of RNA polymerase II transcription preinitiation complex assembly →	+0.132	+0.624	.002	.004	3	10
LUNG_SCLC	rRNA modification →	+0.066	+0.428	<.001	.001	3	10
LUNG_SCLC	Mitochondrial large ribosomal subunit assembly →	+0.105	+0.659	.002	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,240 associations by consensus.

rRNA pseudouridine synthesis by EIF5AL1 expression — LUNG_SCLC

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