EIF5AL1

Across TCGA cell cohorts, EIF5AL1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EIF5AL1-associated genes across cancer lineages are ACOD1 and KRTAP3-2. Each is linked with EIF5AL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EIF5AL1-to-partner and partner-to-EIF5AL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACOD1 grouped by EIF5AL1-low versus EIF5AL1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF5AL1→partner) and Y-score (partner→EIF5AL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ACOD1 →	+0.006	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	KRTAP3-2 →	+0.083	+6.247	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ACOD1 by EIF5AL1 expression — BLOOD_Lymphoma

Explore this box plot interactively →