EIF5A2

Across TCGA cell cohorts, EIF5A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,487 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible EIF5A2-associated GO terms across cancer lineages are Peptidyl-glutamate ADP-deribosylation, Phosphatidylinositol biosynthetic process, and DNA-templated transcription initiation. Each is linked with EIF5A2 in more than 9 cancer types. Because this analysis shows association rather than direction, both EIF5A2-to-partner and partner-to-EIF5A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-glutamate ADP-deribosylation grouped by EIF5A2-low versus EIF5A2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF5A2→partner) and Y-score (partner→EIF5A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Peptidyl-glutamate ADP-deribosylation →	-0.204	-0.920	<.001	.002	3	10
SKIN	Phosphatidylinositol biosynthetic process →	+0.050	+0.851	<.001	<.001	3	10
LARGE_INTESTINE	DNA-templated transcription initiation →	+0.050	+1.010	.004	.002	2	10
LUNG_NSCLC_LUAD	Regulation of post-translational protein modification →	+0.045	+1.408	<.001	<.001	3	9
BREAST	Regulation of extrinsic apoptotic signaling pathway via death domain receptors →	+0.130	+1.468	<.001	<.001	3	9
BLOOD_Lymphoma	Transcription elongation by RNA polymerase II →	+0.055	+1.078	.003	.002	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,487 associations by consensus.

Peptidyl-glutamate ADP-deribosylation by EIF5A2 expression — SOFT_TISSUE

Explore this box plot interactively →