EIF4H

Across TCGA patient cohorts, EIF4H RNA expression is significantly associated with the protein abundance of many other proteins, with 13,206 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EIF4H-associated proteins across cancer lineages are GTF2I, PUS7, and PDAP1. Each is linked with EIF4H in more than 6 cancer types. Because this analysis shows association rather than direction, both EIF4H-to-partner and partner-to-EIF4H results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4H versus GTF2I in HNSC, with a Pearson correlation of 0.24.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4H→partner) and Y-score (partner→EIF4H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GTF2I →	+0.485	+0.587	<.001	.001	3	7
LSCC	PUS7 →	+0.555	+0.498	<.001	<.001	3	7
GBM	PDAP1 →	+0.350	+0.328	<.001	<.001	3	6
COAD	BAZ1B →	+0.308	+0.508	<.001	<.001	3	6
OV	BUD23 →	+0.411	+0.355	.003	.002	3	6
HNSC	DNAJC2 →	+0.355	+1.058	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,206 associations by consensus.

EIF4H vs GTF2I — HNSC

Explore this scatter interactively →