EIF4H

Across TCGA patient cohorts, EIF4H protein abundance is significantly associated with the RNA expression of many other genes, with 9,592 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EIF4H-associated genes across cancer lineages are DBF4, DNAJC2, and CHCHD3. Each is linked with EIF4H in more than 7 cancer types. Because this analysis shows association rather than direction, both EIF4H-to-partner and partner-to-EIF4H results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4H versus DBF4 in UCEC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4H→partner) and Y-score (partner→EIF4H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DBF4 →	+0.862	+0.246	<.001	<.001	3	8
LSCC	DNAJC2 →	+0.519	+0.173	<.001	<.001	3	7
UCEC	CHCHD3 →	+0.919	+0.187	.001	.003	3	7
LSCC	TMEM60 →	+0.616	+0.269	<.001	<.001	3	7
UCEC	RINT1 →	+0.696	+0.262	.001	<.001	3	7
UCEC	COPS6 →	+0.996	+0.285	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,592 associations by consensus.

EIF4H vs DBF4 — UCEC

Explore this scatter interactively →