EIF4H

Across TCGA cell cohorts, EIF4H RNA expression is significantly associated with the go_rna of many other GO terms, with 3,278 significant associations in total. CNS shows the largest number of these associations.

The most reproducible EIF4H-associated GO terms across cancer lineages are Positive regulation of mitotic cell cycle phase transition, Nuclear export, and Chromosome condensation. Each is linked with EIF4H in more than 12 cancer types. Because this analysis shows association rather than direction, both EIF4H-to-partner and partner-to-EIF4H results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitotic cell cycle phase transition grouped by EIF4H-low versus EIF4H-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4H→partner) and Y-score (partner→EIF4H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitotic cell cycle phase transition →	+0.111	+0.935	.001	<.001	3	13
BLOOD_Myeloma	Nuclear export →	+0.069	+0.766	.004	.003	3	13
PANCREAS	Chromosome condensation →	+0.123	+0.710	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Signal transduction in response to DNA damage →	+0.071	+0.619	.001	.008	3	12
LUNG_NSCLC_LUSC	Spindle elongation →	+0.250	+0.457	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Mitotic chromosome condensation →	+0.141	+0.716	.003	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,278 associations by consensus.

Positive regulation of mitotic cell cycle phase transition by EIF4H expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →