EIF4EP3

Across TCGA patient cohorts, EIF4EP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,303 significant associations in total. STAD shows the largest number of these associations.

The most reproducible EIF4EP3-associated GO terms across cancer lineages are Positive regulation of protein catabolic process, tRNA modification, and RNA modification. Each is linked with EIF4EP3 in more than 14 cancer types. Because this analysis shows association rather than direction, both EIF4EP3-to-partner and partner-to-EIF4EP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein catabolic process grouped by EIF4EP3-low versus EIF4EP3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4EP3→partner) and Y-score (partner→EIF4EP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of protein catabolic process →	+0.046	+0.137	<.001	<.001	3	14
STAD	tRNA modification →	+0.046	+0.139	<.001	<.001	3	14
ESCA	RNA modification →	+0.051	+0.309	.009	.001	2	15
STAD	Transport along microtubule →	+0.039	+0.142	<.001	<.001	3	14
STAD	Regulation of ubiquitin-dependent protein catabolic process →	+0.048	+0.123	<.001	<.001	3	13
STAD	Macromolecule methylation →	+0.044	+0.132	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,303 associations by consensus.

Positive regulation of protein catabolic process by EIF4EP3 expression — STAD

Explore this box plot interactively →