EIF4EBP3

Across TCGA patient cohorts, EIF4EBP3 protein abundance is significantly associated with the RNA expression of many other genes, with 4,953 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EIF4EBP3-associated genes across cancer lineages are CENPN, AGBL2, and NUDT12. Each is linked with EIF4EBP3 in more than 3 cancer types. Because this analysis shows association rather than direction, both EIF4EBP3-to-partner and partner-to-EIF4EBP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4EBP3 versus CENPN in OV, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4EBP3→partner) and Y-score (partner→EIF4EBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CENPN →	-0.737	-0.626	<.001	.001	3	4
UCEC	AGBL2 →	+0.850	+0.437	.005	.006	3	4
BRCA	NUDT12 →	+1.070	+0.614	<.001	<.001	3	3
LUAD	CENPA →	-1.181	-0.458	<.001	<.001	3	3
LUAD	HJURP →	-1.327	-0.472	<.001	<.001	3	3
OV	DLGAP5 →	-1.280	-0.694	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,953 associations by consensus.

EIF4EBP3 vs CENPN — OV

Explore this scatter interactively →