EIF4EBP3

Across TCGA cell cohorts, EIF4EBP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,271 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EIF4EBP3-associated GO terms across cancer lineages are Positive regulation of mitotic cell cycle, Centromeric sister chromatid cohesion, and Interstrand cross-link repair. Each is linked with EIF4EBP3 in more than 7 cancer types. Because this analysis shows association rather than direction, both EIF4EBP3-to-partner and partner-to-EIF4EBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitotic cell cycle grouped by EIF4EBP3-low versus EIF4EBP3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4EBP3→partner) and Y-score (partner→EIF4EBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of mitotic cell cycle →	-0.089	-1.737	<.001	.002	3	8
KIDNEY	Centromeric sister chromatid cohesion →	-0.153	-1.913	.002	<.001	3	7
SOFT_TISSUE	Interstrand cross-link repair →	-0.068	-1.372	.001	.001	3	7
UPPER_AERODIGESTIVE_TRACT	Positive regulation of G1/S transition of mitotic cell cycle →	-0.094	-1.413	.001	.007	3	6
BLOOD_Myeloma	Macrophage proliferation →	-1.559	-1.919	<.001	<.001	3	6
BLOOD_Myeloma	Microglial cell proliferation →	-1.559	-1.919	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,271 associations by consensus.

Positive regulation of mitotic cell cycle by EIF4EBP3 expression — STOMACH

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