Across TCGA patient cohorts, EIF4EBP1 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EIF4EBP1-associated genes across cancer lineages are NUDT4B, MIR4499, and MIR4717. Each is linked with EIF4EBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EIF4EBP1-to-partner and partner-to-EIF4EBP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4EBP1→partner) and Y-score (partner→EIF4EBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NUDT4B →	+0.105	+5.621	<.001	.004	3	1
UCEC	MIR4499 →	+0.828	+5.081	<.001	.008	3	1
UCEC	MIR4717 →	+0.625	+6.335	<.001	.001	3	1
UCEC	LONRF2P1 →	+0.088	+5.694	.008	.003	3	1
LUSC	KRTAP2-4 →	+0.057	+7.102	<.001	<.001	3	1
LUSC	MIR4422HG →	+0.142	+5.038	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

EIF4EBP1 survival (RNA) · tumor vs normal (RNA) · all EIF4EBP1 data types