EIF4E2

Across TCGA patient cohorts, EIF4E2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,617 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EIF4E2-associated proteins across cancer lineages are DIS3L2, ICAM3, and ATIC. Each is linked with EIF4E2 in more than 4 cancer types. Because this analysis shows association rather than direction, both EIF4E2-to-partner and partner-to-EIF4E2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4E2 versus DIS3L2 in OV, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4E2→partner) and Y-score (partner→EIF4E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DIS3L2 →	+0.360	+0.404	<.001	<.001	3	5
GBM	ICAM3 →	-0.632	-0.205	<.001	<.001	3	4
LSCC	ATIC →	+0.251	+0.236	<.001	<.001	3	4
LSCC	COPS7B →	+0.243	+0.286	<.001	<.001	3	4
PDAC	COX5B →	-0.403	-0.310	<.001	<.001	3	4
LSCC	EVI2B →	-0.576	-0.310	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,617 associations by consensus.

EIF4E2 vs DIS3L2 — OV

Explore this scatter interactively →