EIF4E2

Across TCGA patient cohorts, EIF4E2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,266 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible EIF4E2-associated genes across cancer lineages are NCL, DTYMK, and COPS7B. Each is linked with EIF4E2 in more than 4 cancer types. Because this analysis shows association rather than direction, both EIF4E2-to-partner and partner-to-EIF4E2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4E2 versus NCL in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4E2→partner) and Y-score (partner→EIF4E2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NCL →	+0.405	+0.229	.001	<.001	3	5
HNSC	DTYMK →	+0.778	+0.189	.002	<.001	3	5
OV	COPS7B →	+0.511	+0.256	<.001	<.001	3	5
OV	PSMD1 →	+0.448	+0.199	.001	.008	2	5
BRCA	PRELP →	-1.372	-0.189	.001	<.001	3	4
OV	CNOT9 →	+0.443	+0.209	.002	.005	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,266 associations by consensus.

EIF4E2 vs NCL — OV

Explore this scatter interactively →