EIF4BP8

Across TCGA pan-cancer cohorts, EIF4BP8 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated EIF4BP8 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher EIF4BP8 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated EIF4BP8 expression acts as an unfavorable survival marker, although some lineages such as KIRC and READ show a favorable association.

KIRC, LIHC, and READ are the cancer types where EIF4BP8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	II,III,IV	0.665	0.444	.002	61	view →
LIHC	DFS	Tertile	All	0.439	0.584	.001	33	view →
READ	DFS	Median	III,IV	0.505	0.241	.014	25	view →
OV	OS	Quartile	II,III,IV	0.292	0.422	.006	20	view →
UCS	DFS	Median	II,III,IV	0.420	0.178	.025	18	view →
BRCA	OS	Tertile	II,III,IV	0.472	0.569	.018	16	view →
KIRP	DFS	Quartile	All	0.502	0.715	.010	16	view →
THCA	OS	Quartile	II,III,IV	1.000	0.813	.021	14	view →
STAD	OS	Tertile	IV	0.662	0.190	.017	12	view →
SKCM	OS	Median	All	0.496	0.293	.005	8	view →
UCEC	OS	Median	II,III,IV	0.801	0.899	.015	8	view →
GBM	DFS	Quartile	All	0.431	0.186	.010	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

EIF4BP8–KIRC (DFS)

Open the KIRC breakdown →