EIF4A2P4

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, EIF4A2P4 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated EIF4A2P4 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher EIF4A2P4 RNA is associated with better overall survival. In most high-consensus cancer types, elevated EIF4A2P4 expression acts as an unfavorable survival marker, although some lineages such as LUSC and THCA show a favorable association.

LUSC, THCA, and UCS are the cancer types where EIF4A2P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUSCOSTertileAll0.8290.689.00144view →
THCADFSMedianAll0.9590.909.00135view →
UCSDFSMedianIV0.8850.440.01530view →
SKCMOSQuartileAll0.3900.229<.00129view →
STADDFSTertileIV0.1630.737<.00124view →
BRCADFSMedianAll0.4920.566.01721view →
ESCADFSMedianIV0.2050.634.00618view →
READDFSMedianAll0.8190.366.00118view →
BLCADFSTertileIV0.3770.602.01116view →
PAADOSQuartileAll0.2150.544.00215view →
ACCOSQuartileIV0.8760.363.00613view →
LGGOSMedianAll0.3380.542.00312view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

Exploration