EIF4A2

Across TCGA patient cohorts, EIF4A2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,379 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EIF4A2-associated genes across cancer lineages are PFN1, TNFRSF1B, and ZNF853. Each is linked with EIF4A2 in more than 4 cancer types. Because this analysis shows association rather than direction, both EIF4A2-to-partner and partner-to-EIF4A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4A2 versus PFN1 in COAD, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4A2→partner) and Y-score (partner→EIF4A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PFN1 →	-0.456	-0.256	.001	<.001	3	5
OV	TNFRSF1B →	-0.983	-0.419	<.001	<.001	3	4
HNSC	ZNF853 →	+0.618	+0.269	<.001	.001	3	4
GBM	CBX7 →	+0.685	+0.256	<.001	<.001	3	4
OV	COTL1 →	-0.730	-0.325	<.001	<.001	3	3
PDAC	NCF2 →	-0.604	-0.213	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,379 associations by consensus.

EIF4A2 vs PFN1 — COAD

Explore this scatter interactively →