EIF4A2

Across TCGA cell cohorts, EIF4A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,734 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible EIF4A2-associated GO terms across cancer lineages are Protein desumoylation, Response to arsenite ion, and Cellular response to arsenite ion. Each is linked with EIF4A2 in more than 14 cancer types. Because this analysis shows association rather than direction, both EIF4A2-to-partner and partner-to-EIF4A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein desumoylation grouped by EIF4A2-low versus EIF4A2-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4A2→partner) and Y-score (partner→EIF4A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Protein desumoylation →	+0.096	+0.569	<.001	.001	3	15
LUNG_NSCLC_LUSC	Response to arsenite ion →	+0.109	+1.158	.005	<.001	3	14
LUNG_NSCLC_LUSC	Cellular response to arsenite ion →	+0.109	+1.158	.005	<.001	3	14
LUNG_NSCLC_LUSC	Maintenance of centrosome location →	+0.132	+0.805	<.001	<.001	3	13
OVARY	Protein modification by small protein removal →	+0.051	+0.761	<.001	.005	3	9
UPPER_AERODIGESTIVE_TRACT	Spliceosomal complex assembly →	+0.089	+0.932	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,734 associations by consensus.

Protein desumoylation by EIF4A2 expression — BLOOD_Leukemia

Explore this box plot interactively →