EIF4A1P7

Across TCGA pan-cancer cohorts, EIF4A1P7 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated EIF4A1P7 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher EIF4A1P7 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated EIF4A1P7 expression acts as an unfavorable survival marker, although some lineages such as COAD and READ show a favorable association.

UVM, STAD, and COAD are the cancer types where EIF4A1P7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Median	III,IV	0.381	0.804	<.001	55	view →
STAD	OS	Tertile	II,III,IV	0.490	0.785	.005	49	view →
COAD	DFS	Median	All	0.603	0.388	<.001	45	view →
SARC	DFS	Quartile	All	0.476	0.684	<.001	31	view →
UCS	DFS	Median	III,IV	0.141	0.500	.004	28	view →
PAAD	OS	Median	All	0.325	0.591	.001	21	view →
READ	DFS	Median	III,IV	0.871	0.618	.002	21	view →
ACC	DFS	Quartile	II,III,IV	0.284	0.871	.005	19	view →
MESO	DFS	Median	II,III,IV	0.497	0.318	.019	13	view →
CESC	DFS	Tertile	All	0.810	0.669	.020	10	view →
LGG	OS	Tertile	All	0.881	0.946	.008	10	view →
KIRP	DFS	Quartile	IV	0.687	0.036	.024	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

EIF4A1P7–UVM (OS)

Open the UVM breakdown →