EIF4A1P7

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, EIF4A1P7 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of EIF4A1P7’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where EIF4A1P7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types EIF4A1P7 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

COAD, KIRP, and KIRC are the cancer types where EIF4A1P7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EIF4A1P7 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
COADAllII,III,IV+0.510<.0018view →
KIRPAllAll+0.083<.0017view →
KIRCMaleAll+0.078<.0017view →
HNSCAllAll+0.100.0036view →
UCECAllAll+0.283.0162view →
READAllIII,IV+0.280.0422view →
PRADAllAll+0.109.0012view →
LUSCAllAll+0.074.0112view →
STADAllII,III,IV+0.156.0341view →
CHOLAllAll+0.095.0291view →
LUADAllAll+0.094.0231view →
LIHCFemaleII,III,IV+0.055.0291view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

EIF4A1P7–COAD

Tumor-vs-normal expression box plot for EIF4A1P7 RNA in COAD.

Open the COAD breakdown →

Exploration