EIF4A1P12

Across TCGA pan-cancer cohorts, EIF4A1P12 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated EIF4A1P12 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher EIF4A1P12 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated EIF4A1P12 expression acts as an unfavorable survival marker, although some lineages such as BRCA and SKCM show a favorable association.

KIRC, ACC, and COAD are the cancer types where EIF4A1P12 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.410	0.649	.001	90	view →
ACC	DFS	Tertile	III,IV	0.010	0.458	<.001	81	view →
COAD	OS	Tertile	IV	0.281	0.682	.001	39	view →
UVM	OS	Tertile	III,IV	0.075	0.814	<.001	36	view →
LGG	DFS	Tertile	All	0.602	0.758	<.001	36	view →
LIHC	DFS	Tertile	III,IV	0.048	0.339	<.001	27	view →
THCA	DFS	Tertile	II,III,IV	0.145	0.794	.001	18	view →
BRCA	OS	Tertile	III,IV	0.931	0.805	.021	18	view →
CHOL	OS	Tertile	All	0.279	0.735	.011	9	view →
MESO	OS	Tertile	IV	0.384	0.634	.023	9	view →
THYM	OS	Tertile	All	0.775	0.973	.031	6	view →
CESC	DFS	Tertile	All	0.705	0.832	.029	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

EIF4A1P12–KIRC (OS)

Open the KIRC breakdown →