EIF4A1P12

Across TCGA pan-cancer cohorts, EIF4A1P12 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of EIF4A1P12’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where EIF4A1P12 RNA is repressed in tumor relative to normal tissue. In most cancer types EIF4A1P12 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

BRCA, BLCA, and KIRC are the cancer types where EIF4A1P12 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EIF4A1P12 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	−0.483	<.001	6	view →
BLCA	All	III,IV	+0.207	.046	3	view →
KIRC	All	All	+0.026	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

EIF4A1P12–BRCA

Open the BRCA breakdown →