EIF4A1P1

Across TCGA patient cohorts, EIF4A1P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,392 significant associations in total. STAD shows the largest number of these associations.

The most reproducible EIF4A1P1-associated GO terms across cancer lineages are Positive regulation of mRNA metabolic process, Protein-containing complex disassembly, and Regulation of mRNA catabolic process. Each is linked with EIF4A1P1 in more than 14 cancer types. Because this analysis shows association rather than direction, both EIF4A1P1-to-partner and partner-to-EIF4A1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mRNA metabolic process grouped by EIF4A1P1-low versus EIF4A1P1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4A1P1→partner) and Y-score (partner→EIF4A1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of mRNA metabolic process →	+0.061	+0.082	.002	.001	3	15
STAD	Protein-containing complex disassembly →	+0.046	+0.091	<.001	<.001	3	14
ESCA	Regulation of mRNA catabolic process →	+0.052	+0.069	.004	.002	2	15
STAD	rRNA metabolic process →	+0.057	+0.114	<.001	<.001	3	13
STAD	Regulation of protein ubiquitination →	+0.051	+0.108	<.001	<.001	3	13
STAD	RNA localization →	+0.058	+0.104	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,392 associations by consensus.

Positive regulation of mRNA metabolic process by EIF4A1P1 expression — ESCA

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