EIF4A1

Across TCGA patient cohorts, EIF4A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,354 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EIF4A1-associated proteins across cancer lineages are NUP214_S678, SMG9_S32, and ELAC2. Each is linked with EIF4A1 in more than 4 cancer types. Because this analysis shows association rather than direction, both EIF4A1-to-partner and partner-to-EIF4A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4A1 versus NUP214_S678 in CCRCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4A1→partner) and Y-score (partner→EIF4A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NUP214_S678 →	+0.334	+0.654	.002	<.001	3	5
CCRCC	SMG9_S32 →	-0.335	-0.419	<.001	.001	3	4
LSCC	ELAC2 →	+0.311	+0.307	.007	.004	3	4
CCRCC	COIL_S487 →	+0.572	+0.480	.001	<.001	3	4
LSCC	MYBBP1A →	+0.407	+0.419	<.001	<.001	3	4
LSCC	UBE2G1 →	+0.326	+0.400	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,354 associations by consensus.

EIF4A1 vs NUP214_S678 — CCRCC

Explore this scatter interactively →