EIF4A1

Across TCGA patient cohorts, EIF4A1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,548 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EIF4A1-associated genes across cancer lineages are KIF20A, NCAPH, and KIF18A. Each is linked with EIF4A1 in more than 7 cancer types. Because this analysis shows association rather than direction, both EIF4A1-to-partner and partner-to-EIF4A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF4A1 versus KIF20A in UCEC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF4A1→partner) and Y-score (partner→EIF4A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KIF20A →	+1.166	+0.275	<.001	<.001	3	8
UCEC	NCAPH →	+1.003	+0.333	<.001	<.001	3	8
BRCA	KIF18A →	+0.758	+0.165	<.001	.004	3	8
UCEC	SGO1 →	+1.058	+0.329	<.001	<.001	3	8
GBM	CENPE →	+0.741	+0.153	.001	.004	3	8
UCEC	CDCA5 →	+1.501	+0.279	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,548 associations by consensus.

EIF4A1 vs KIF20A — UCEC

Explore this scatter interactively →