EIF3J

Across TCGA patient cohorts, EIF3J mutation is significantly associated with the RNA expression of many other genes, with 2,090 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EIF3J-associated genes across cancer lineages are LIN7C, EIF3M, and COX15. Each is linked with EIF3J in more than 1 cancer types. Because this analysis shows association rather than direction, both EIF3J-to-partner and partner-to-EIF3J results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LIN7C grouped by EIF3J-low versus EIF3J-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3J→partner) and Y-score (partner→EIF3J) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LIN7C →	+0.433	+1.934	.007	.002	3	1
UCEC	EIF3M →	+0.422	+1.906	.002	.001	3	1
UCEC	COX15 →	+0.446	+2.095	<.001	.003	3	1
UCEC	INTS4 →	+0.316	+2.233	.002	<.001	3	1
UCEC	LAMTOR1 →	+0.394	+2.595	<.001	<.001	3	1
UCEC	TKFC →	+0.380	+1.595	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,090 associations by consensus.

LIN7C by EIF3J expression — UCEC

Explore this box plot interactively →