EIF3J

Across TCGA cell cohorts, EIF3J RNA expression is significantly associated with the go_rna of many other GO terms, with 3,552 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EIF3J-associated GO terms across cancer lineages are Formation of cytoplasmic translation initiation complex, Protein localization to kinetochore, and Protein localization to condensed chromosome. Each is linked with EIF3J in more than 14 cancer types. Because this analysis shows association rather than direction, both EIF3J-to-partner and partner-to-EIF3J results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Formation of cytoplasmic translation initiation complex grouped by EIF3J-low versus EIF3J-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3J→partner) and Y-score (partner→EIF3J) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Formation of cytoplasmic translation initiation complex →	+0.129	+0.926	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Protein localization to kinetochore →	+0.165	+0.895	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Protein localization to condensed chromosome →	+0.148	+0.767	.001	.003	3	14
UPPER_AERODIGESTIVE_TRACT	Protein localization to chromosome, centromeric region →	+0.123	+0.773	.001	<.001	3	14
LUNG_SCLC	Pseudouridine synthesis →	+0.073	+0.646	.002	<.001	3	14
SKIN	Ubiquitin-dependent protein catabolic process via the N-end rule pathway →	+0.079	+0.737	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,552 associations by consensus.

Formation of cytoplasmic translation initiation complex by EIF3J expression — PANCREAS

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