EIF3J-DT

Across TCGA pan-cancer cohorts, EIF3J-DT RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated EIF3J-DT data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher EIF3J-DT RNA is associated with better overall survival. In most high-consensus cancer types, elevated EIF3J-DT expression acts as an unfavorable survival marker, although some lineages such as KIRC and READ show a favorable association.

KIRC, COAD, and READ are the cancer types where EIF3J-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.701	0.559	<.001	119	view →
COAD	OS	Median	All	0.525	0.697	.001	92	view →
READ	OS	Median	II,III,IV	0.823	0.390	<.001	53	view →
LIHC	DFS	Median	All	0.474	0.609	<.001	39	view →
BRCA	OS	Tertile	III,IV	0.973	0.819	<.001	39	view →
ACC	DFS	Tertile	All	0.304	0.777	<.001	29	view →
SKCM	DFS	Median	All	0.239	0.170	.004	24	view →
KIRP	DFS	Tertile	IV	0.038	0.529	.006	24	view →
UVM	DFS	Tertile	III,IV	0.209	1.000	.001	20	view →
UCS	DFS	Quartile	II,III,IV	0.527	0.065	.011	20	view →
CHOL	DFS	Tertile	All	0.697	0.260	.006	12	view →
UCEC	OS	Quartile	III,IV	0.796	0.464	.021	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

EIF3J-DT–KIRC (OS)

Open the KIRC breakdown →