EIF3J-DT

Across TCGA pan-cancer cohorts, EIF3J-DT RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of EIF3J-DT’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where EIF3J-DT RNA is repressed in tumor relative to normal tissue. In most cancer types EIF3J-DT is over-expressed in tumor, although a few such as LUAD and KICH show the opposite, repressed pattern.

LUAD, KICH, and LIHC are the cancer types where EIF3J-DT tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EIF3J-DT RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	III,IV	−0.617	<.001	10	view →
KICH	Female	All	−1.303	<.001	8	view →
LIHC	Female	All	+0.672	<.001	8	view →
LUSC	All	All	−0.363	<.001	7	view →
UCEC	All	All	−1.175	<.001	6	view →
BRCA	Female	II,III,IV	−0.644	<.001	6	view →
CHOL	All	All	+2.027	<.001	5	view →
KIRC	All	II,III,IV	−0.376	.009	5	view →
COAD	All	All	+0.348	.004	4	view →
THCA	Male	II,III,IV	−0.273	.008	3	view →
BLCA	Male	IV	−0.892	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

EIF3J-DT–LUAD

Open the LUAD breakdown →