EIF3H

Across TCGA pan-cancer cohorts, EIF3H Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated EIF3H data layer compared with 25 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher EIF3H Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated EIF3H expression acts as an unfavorable survival marker.

SKCM, CHOL, and LIHC are the cancer types where EIF3H Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Median	IV	0.028	0.477	<.001	12	view →
CHOL	OS	Median	All	0.155	0.725	.029	3	view →
LIHC	OS	Median	All	0.152	0.704	.022	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

EIF3H–SKCM (DFS)

Open the SKCM breakdown →