EIF3H

Across TCGA pan-cancer cohorts, EIF3H mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated EIF3H data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher EIF3H mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated EIF3H expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

LUAD, HNSC, and GBM are the cancer types where EIF3H mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	III,IV	0.862	0.262	.008	21	view →
HNSC	OS	Median	All	1.000	0.449	.023	8	view →
GBM	DFS	Tertile	All	0.299	0.442	.023	5	view →
OV	DFS	Median	All	1.000	0.864	.036	4	view →
PDAC	DFS	Tertile	All	0.854	0.652	.018	4	view →
LSCC	DFS	Tertile	All	1.000	0.586	.030	3	view →
CCRCC	DFS	Median	III,IV	0.774	0.207	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

EIF3H–LUAD (DFS)

Open the LUAD breakdown →