EIF3H

Across TCGA cell cohorts, EIF3H mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EIF3H-associated genes across cancer lineages are VAX1, SSMEM1, and PRND. Each is linked with EIF3H in more than 1 cancer types. Because this analysis shows association rather than direction, both EIF3H-to-partner and partner-to-EIF3H results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VAX1 grouped by EIF3H-low versus EIF3H-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3H→partner) and Y-score (partner→EIF3H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	VAX1 →	+0.742	+3.519	<.001	.007	3	1
LARGE_INTESTINE	SSMEM1 →	+0.023	+3.029	.001	.006	3	1
LARGE_INTESTINE	PRND →	+0.021	+2.878	.005	.009	3	1
LARGE_INTESTINE	OR2T8 →	+0.139	+3.584	.004	.004	3	1
LARGE_INTESTINE	TAFA1 →	+0.234	+3.103	.002	.004	3	1
LARGE_INTESTINE	PNMA3 →	+0.194	+2.781	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

VAX1 by EIF3H expression — LARGE_INTESTINE

Explore this box plot interactively →