EIF3E

Across TCGA patient cohorts, EIF3E mutation is significantly associated with the RNA expression of many other genes, with 3,513 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EIF3E-associated genes across cancer lineages are RNU6-1169P, RMDN1, and WDFY2. Each is linked with EIF3E in more than 2 cancer types. Because this analysis shows association rather than direction, both EIF3E-to-partner and partner-to-EIF3E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1169P grouped by EIF3E-low versus EIF3E-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3E→partner) and Y-score (partner→EIF3E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-1169P →	+0.581	+4.399	<.001	.006	3	3
UCEC	RMDN1 →	+0.331	+2.329	.002	.003	3	2
UCEC	WDFY2 →	+0.421	+1.895	<.001	.001	3	2
LUSC	RNU6-918P →	+0.483	+3.861	<.001	.001	3	2
UCEC	C8orf33 →	+0.470	+2.212	.004	<.001	3	2
COAD	PSAT1P4 →	+0.420	+4.785	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,513 associations by consensus.

RNU6-1169P by EIF3E expression — LUAD

Explore this box plot interactively →