EIF3E

Across TCGA cell cohorts, EIF3E mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EIF3E-associated genes across cancer lineages are ITGAD, CFAP47, and WDR87. Each is linked with EIF3E in more than 1 cancer types. Because this analysis shows association rather than direction, both EIF3E-to-partner and partner-to-EIF3E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ITGAD grouped by EIF3E-low versus EIF3E-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3E→partner) and Y-score (partner→EIF3E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ITGAD →	+0.011	+3.510	<.001	.003	3	1
LARGE_INTESTINE	CFAP47 →	+0.368	+3.453	<.001	.009	3	1
LARGE_INTESTINE	WDR87 →	+0.021	+3.453	<.001	.009	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.010	+4.022	<.001	.006	3	1
LARGE_INTESTINE	TBC1D3K →	+0.367	+3.781	<.001	.003	3	1
BLOOD_Lymphoma	CABP5 →	+0.014	+5.452	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

ITGAD by EIF3E expression — LARGE_INTESTINE

Explore this box plot interactively →