EIF3CL

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, EIF3CL RNA expression is significantly associated with the go_rna of many other GO terms, with 2,651 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EIF3CL-associated GO terms across cancer lineages are Formation of cytoplasmic translation initiation complex, Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), and Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with EIF3CL in more than 15 cancer types. Because this analysis shows association rather than direction, both EIF3CL-to-partner and partner-to-EIF3CL results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF3CL→partner) and Y-score (partner→EIF3CL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINFormation of cytoplasmic translation initiation complex →+0.120+0.918<.001<.001316
UPPER_AERODIGESTIVE_TRACTMaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →+0.110+0.694.001.004312
STOMACHMaturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →+0.074+0.627.002.003213
CNSNucleolar large rRNA transcription by RNA polymerase I →+0.103+0.688<.001<.001312
UPPER_AERODIGESTIVE_TRACTMaturation of SSU-rRNA →+0.110+0.720.001.004311
CNSTranscription initiation at RNA polymerase I promoter →+0.100+0.779<.001<.001311
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,651 associations by consensus.

Exploration